In this free webinar, learn how to design more effective central nervous system (CNS) drug delivery studies and avoid common pitfalls in the field. Attendees will gain insights into techniques for direct injection into specific brain regions and intrathecal spaces. The featured speakers will discuss novel techniques in visualizing gene transport using fluorescent tagging and tomography imaging. Attendees will also learn about the measurement of biodistribution and biological endpoints in CNS studies. Additionally, the speakers will discuss the role of MRI guidance in ensuring accurate drug delivery and minimizing off-target effects.
TORONTO, March 31, 2025 /PRNewswire-PRWeb/ -- In this webinar, the attendees will gain insights into the latest research methodologies used to optimize central nervous system (CNS)-targeted drug delivery.
A key highlight of the webinar will be the presentation of novel data from a pilot study. This study utilized adeno-associated virus (AAV)-based gene therapy with fluorescent tagging, allowing for advanced visualization of biodistribution through histological and tomography-based imaging techniques.
During the webinar, the speakers will discuss a groundbreaking approach where a fluorescent-tagged transgene was delivered via AAV to the brain, enabling visualization using histological techniques and tomography imaging. This innovative approach allowed researchers to generate highly detailed 3D reconstructions of biodistribution patterns, layered with magnetic resonance imaging (MRI) anatomical data to create a comprehensive visualization of gene transport. This type of data is invaluable for researchers designing CNS-targeted drug delivery programs as it provides both qualitative and quantitative insights into treatment efficacy and precision.
The webinar will also address translational considerations for CNS drug delivery. The speakers' insights will be particularly valuable for professionals looking to bridge the gap between preclinical research and clinical implementation.
Register for this webinar to gain a clear understanding of how to design more effective CNS drug delivery studies and avoid common pitfalls in the field.
Join Jake McDonald, PhD, ATS, CEO, Envol Biomedical; Dr. Reinier Espinosa, Lead Surgeon and Study Director, Envol Biomedical; and Dr. Ernesto Salegio, PhD, Vice President, Segment Leader Translational & Pre-Clinical Research, ClearPoint Neuro, for the live webinar on Wednesday, April 16, 2025, at 11am EDT (4pm BST/UK).
For more information, or to register for this event, visit Advanced Drug Delivery to the Central Nervous System in Nonhuman Primates.
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