Applications of Multiplex Immunofluorescence for Immune Biomarkers in Drug Development, Upcoming Webinar Hosted by Xtalks
In this free webinar, the featured speakers will discuss the current challenges in drug development and how Invicro, a Konica Minolta Company, applies domain expertise to help pharma sponsors address them. They will highlight the limitations of conventional immunohistochemistry (IHC) methods and discuss how multiplex fluorescent assays can be deployed to detect biomarkers and characterize immune cells in the tissue microenvironment. The speakers will present the utility of novel research tools and methods to answer specific biological questions.
TORONTO, April 8, 2021 /PRNewswire-PRWeb/ -- Immune infiltration in the tissue microenvironment is a hallmark of many disease indications, including cancer, autoimmune disease, degenerative conditions and others. Monitoring changes in immune heterogeneity according to disease state, or treatment with a drug is critical to understand disease etiology and predicting response to treatments.
The multiple cell phenotypes of immune cells can be interrogated simultaneously on the same formalin-fixed paraffin-embedded (FFPE) section using multiplex immunohistochemistry (m-IHC). As such, multiplex immunofluorescence (m-IF) assays have become an established approach to measure immune biomarkers, from early discovery to exploratory endpoint testing in clinical trials. Despite the high utility of these assays, development and optimization is difficult due to the high complexity and need for deep domain and technical expertise.
Register for this webinar to hear experts from Invicro discuss the current challenges using these approaches encountered in biomarker discovery and development programs. Specifically, you will learn how using a combination of m-IHC and multispectral image analysis approaches can uncover insights needed to accelerate the development of tailored therapies.
Join Invicro experts, Joseph Krueger, Ph.D., VP of Research & Applications, Advanced Pathology Services; and Amanda Bares, Ph.D., Senior Scientist, Advanced Pathology Services, for the live webinar on Wednesday, April 28, 2021 at 1pm EDT (10am PDT).
For more information, or to register for this event, visit Applications of Multiplex Immunofluorescence for Immune Biomarkers in Drug Development.
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