As scientific interest in psychedelic-assisted therapies continues to surge, MindScape Retreat, a licensed Ibogaine treatment facility located on the peaceful island of Cozumel, Mexico, is establishing itself as the global leader in Ibogaine-based neurotherapy. With a growing body of clinical case studies and a scientifically integrated treatment protocol, MindScape is advancing care for complex disorders including Parkinson's disease, PTSD, treatment-resistant depression, anxiety, SSRI tapering, addiction, OCD, and multiple sclerosis (MS).
COZUMEL, Mexico, April 23, 2025 /PRNewswire-PRWeb/ -- As scientific interest in psychedelic-assisted therapies continues to surge, MindScape Retreat, a licensed Ibogaine treatment center located on the peaceful island of Cozumel, Mexico, is establishing itself as the global leader in Ibogaine-based neurotherapy. With a growing body of clinical case studies and a scientifically integrated treatment protocol, MindScape is advancing care for complex disorders including Parkinson's disease, PTSD, treatment-resistant depression, anxiety, SSRI tapering, addiction, OCD, and multiple sclerosis (MS).
Clinical Research and Case Study Development
In collaboration with international medical researchers and academic consultants, MindScape Retreat is conducting a comprehensive, data-driven case study series to evaluate the safety and efficacy of Ibogaine for both neurological and psychiatric indications. Each patient undergoing treatment for conditions like Parkinson's or PTSD is monitored through:
- Unified Parkinson's Disease Rating Scale (UPDRS)
- Montreal Cognitive Assessment (MoCA)
- Hamilton Depression Rating Scale (HAM-D)
- State-Trait Anxiety Inventory (STAI)
- Timed Up & Go (TUG) Test
- Pre- and post-treatment blood biomarkers for neuroinflammation and oxidative stress
These measures are part of a prospective cohort design that tracks changes in motor function, mood, cognitive performance, and quality of life. The retreat plans to submit its first peer-reviewed publication by mid-2025, presenting outcomes from over 30 patients across multiple diagnostic categories. Early data indicates notable improvements in motor symptoms for Parkinson's patients, significant reduction in PTSD symptom clusters, and successful discontinuation of SSRIs in long-term users.
How Ibogaine Works: Neuroregeneration at the Molecular Level
Unlike conventional pharmacotherapy, which often targets symptoms through receptor blocking or neurotransmitter reuptake inhibition, Ibogaine acts systemically, promoting long-term neural repair and functional restoration. Scientifically, its mechanisms of action include:
- Stimulation of Glial Cell-Derived Neurotrophic Factor (GDNF): Essential for dopaminergic neuron survival, GDNF supports repair in Parkinson's disease and dopamine depletion from addiction or SSRI withdrawal.
- Increase in Brain-Derived Neurotrophic Factor (BDNF): Promotes synaptic plasticity and neurogenesis, beneficial for cognitive restoration in trauma-related disorders and neurodegeneration.
- Dopaminergic and Serotonergic Modulation: Ibogaine resets dysregulated dopamine and serotonin pathways, which are central to mood, motivation, addiction, and obsessive-compulsive patterns.
- NMDA Receptor Antagonism: Reduces excitotoxicity and neuroinflammation, two key contributors to progressive neurological diseases.
The therapy is further enhanced with NAD⁺ infusions, which improve mitochondrial energy metabolism and cellular repair, and 5-MeO-DMT therapy, offering an emotional integration experience post-Ibogaine.
Why Cozumel? Safety and Serenity for Healing
While Ibogaine treatment has gained attention in cities like Tijuana and Cancun, MindScape Retreat's location in Cozumel provides unmatched safety, privacy, and tranquility. Unlike border cities known for higher crime rates or medical tourism saturation, Cozumel is an island sanctuary, offering:
- A secure and peaceful environment, away from the overstimulation of urban areas.
- Consistent access to emergency medical support and direct collaboration with nearby hospitals.
- Fully licensed, government-compliant protocols, ensuring legal and ethical treatment standards.
This geographical advantage allows for deeper patient focus, tighter medical supervision, and reduced risk of environmental stress, which is critical during intensive psychedelic therapy.
What's Next for MindScape Retreat
With its forthcoming case study publication and partnerships with international researchers, MindScape Retreat aims to be at the forefront of psychedelic science applied to neurodegeneration and complex mental health disorders. As regulatory conversations around Ibogaine expand in the U.S., MindScape continues to offer a gold-standard, evidence-based model for how this powerful medicine can be responsibly administered.
For media inquiries, research collaborations, or treatment inquiries, contact:
+1 786-761-7729
https://www.mindscaperetreat.com/ibogaine-treatment-clinic
About MindScape Retreat:
MindScape Retreat is a fully licensed and medically supervised Ibogaine treatment center in Cozumel, Mexico. The center specializes in treating neurological and mental health conditions through Ibogaine, 5-MeO-DMT, and NAD⁺ protocols, supported by rigorous scientific methodology and holistic wellness practices.
Media Contact
Dr Calderon, MindScape Retreat, 1 786-761-7729, [email protected], https://www.mindscaperetreat.com/ibogaine-treatment-clinic
SOURCE MindScape Retreat

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